2015 Spring Colloquium with Sally W. Thurston, PhD
January 22, 2015
Helen Wood Hall - Auditorium 1W304
University of Rochester School of Medicine and Dentistry
Department of Biostatistics and Computational Biology
University of Rochester
“Bayesian Models for Multiple Outcomes in Domains with Application to the Seychelles Child Development Study”
Thursday, January 22, 2015
3:30 P.M. – 5:00 p.m.
New Location - Helen Wood Hall – Auditorium 1W304
(updated on 01/20/2015)
The Seychelles Child Development Study (SCDS) examines the effects of prenatal exposure to methylmercury on the functioning of the central nervous system. The SCDS data include 20 outcomes measured on 9-year old children that can be classified broadly in four outcome classes or "domains": cognition, memory, motor, and social behavior. We first consider the problem of estimating the effect of exposure on multiple outcomes in a single model when each outcome belongs to one domain and domain memberships are known. We then extend this to the situation in which the outcomes may belong to more than one domain and where we also want to learn about the assignment of outcomes to domains. In this talk I will discuss the Seychelles data, motivate and give results of the models with the aid of pictures, and very briefly compare these models to a structural equation model.