Publications

Kennedy Lab research coming soon – we launch January 2020!

Prior to UR

9. Kennedy, C. R.; Zhang, H.; Macaulay, R. L.; Chirik, P. J.* Regio- and Diastereoselective Iron-Catalyzed [4+4]-Cycloaddition of 1,3-Dienes. J. Am. Chem. Soc. 2019, 141, 8557–8573. DOI: 10.1021/jacs.9b02443

Image reproduced with permission. © ACS 2019

8. Schmidt, V. A.; Kennedy, C. R.; Bezdek, M. J.; Chirik, P. J.* Selective [1,4]-Hydrovinylation of 1,3-Dienes with Unactivated Olefins Enabled by Iron Diimine Catalysts. J. Am. Chem. Soc. 2018, 140, 3443–3453. DOI: 10.1021/jacs.8b00245

Image modified with permission. © ACS 2018

7. Klausen, R. S.; Kennedy, C. R.; Hyde, A. M.; Jacobsen, E. N.* Chiral Thioureas Promote Enantioselective Pictet–Spengler Cyclization by Stabilizing Every Intermediate and Transition State in the Carboxylic Acid-Catalyzed Reaction. J. Am. Chem. Soc. 2017139, 12299–12309. DOI: 10.1021/jacs.7b06811

Modified with permission. © ACS 2017

6. Kennedy, C. R.; Lehnherr, D.; Rajapaksa, N. S.; Ford, D. D.; Park, Y.; Jacobsen, E. N.* Mechanism-Guided Development of a Highly Active Bis-thiourea Catalyst for Anion-Abstraction Catalysis. J. Am. Chem. Soc. 2016138, 13525–13528. DOI: 10.1021/jacs.6b09205

Modified with permission. © ACS 2016

5. Kennedy, C. R.; Guidera, J. A.§; Jacobsen, E. N.* Synergistic Ion-Binding Catalysis Demonstrated via an Enantioselective, Catalytic [2,3]-Wittig Rearrangement. ACS Cent. Sci.20162, 416–423. DOI: 10.1021/acscentsci.6b00125

Modified with permission. © ACS 2016

4. Lehnherr, D.; Ford, D. D.; Bendelsmith, A. J.; Kennedy, C. R.; Jacobsen, E. N.* Conformational Control of Chiral Amido-Thiourea Catalysts Enables Improved Activity and Enantioselectivity. Org. Lett. 201618, 3214–3217. DOI:10.1021/acs.orglett.6b01435

3. Ford, D. D.; Lehnherr, D.; Kennedy, C. R.; Jacobsen, E. N.* Anion-Abstraction Catalysis: The Cooperative Mechanism of α-Chloroether Activation by Dual Hydrogen-Bond Donors. ACS Catal. 20166, 4616–4620. DOI: 10.1021/acscatal.6b01384

2. Ford, D. D.; Lehnherr, D.; Kennedy, C. R.; Jacobsen, E. N.* On- and Off-Cycle Catalyst Cooperativity in Anion-Binding Catalysis. J. Am. Chem. Soc. 2016138, 7860–7863. DOI:10.1021/jacs.6b04686

1. Kennedy, C. R.; Lin, S.; Jacobsen, E. N.* The Cation-π Interaction in Small-Molecule Catalysis. Angew. Chem. Int. Ed. 201655, 12596–12624. DOI: 10.1002/anie.201600547

‡ Equal contributions. § Undergraduate coauthor. * Corresponding Author

Find Rose’s ORCID (0000-0003-3681-819X), Google Scholar, and My NCBI pages.