{"id":9722,"date":"2024-04-25T17:27:15","date_gmt":"2024-04-25T21:27:15","guid":{"rendered":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/?page_id=9722"},"modified":"2024-04-25T17:28:02","modified_gmt":"2024-04-25T21:28:02","slug":"yuan-liang","status":"publish","type":"page","link":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/team\/yuan-liang\/","title":{"rendered":"Yuan Liang"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"9722\" class=\"elementor elementor-9722\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4090ae4 e-flex e-con-boxed e-con e-parent\" data-id=\"4090ae4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-0933aac e-con-full e-flex e-con e-child\" data-id=\"0933aac\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e8ef535 elementor-widget elementor-widget-image\" data-id=\"e8ef535\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"640\" height=\"802\" src=\"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-content\/uploads\/2024\/02\/Liang-Yuan-817x1024.jpg\" class=\"attachment-large size-large wp-image-4132\" alt=\"\" srcset=\"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-content\/uploads\/2024\/02\/Liang-Yuan-817x1024.jpg 817w, https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-content\/uploads\/2024\/02\/Liang-Yuan-239x300.jpg 239w, https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-content\/uploads\/2024\/02\/Liang-Yuan-768x962.jpg 768w, https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-content\/uploads\/2024\/02\/Liang-Yuan-1226x1536.jpg 1226w, https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-content\/uploads\/2024\/02\/Liang-Yuan-1635x2048.jpg 1635w, https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-content\/uploads\/2024\/02\/Liang-Yuan-scaled.jpg 2043w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4d0547e e-con-full e-flex e-con e-child\" data-id=\"4d0547e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0fba3cc elementor-widget elementor-widget-text-editor\" data-id=\"0fba3cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>What\u2019s the mechanism of aging? The Sirtuin family members are renowned for their roles in regulating lifespan. Out of the seven mammalian Sirtuins, it is Sirt6 that plays the most critical role. Sirt6 whole-body overexpression has been rigorously shown to extend mice lifespan 15 to 27 percent depending on the gender and strain, and Sirt6 whole-body knockout mice can\u2019t survive over one month. As long as its molecular activities, cellular functions and their physiological relevance are fully comprehended, we will get closer to unveil the mystery. In this lab, my project is to characterize a Sirt6 separation of function mutant mice.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>What\u2019s the mechanism of aging? The Sirtuin family members are renowned for their roles in regulating lifespan. Out of the seven mammalian Sirtuins, it is Sirt6 that plays the most critical role. Sirt6 whole-body overexpression has been rigorously shown to extend mice lifespan 15 to 27 percent depending on the gender and strain, and Sirt6 [&hellip;]<\/p>\n","protected":false},"author":52,"featured_media":0,"parent":246,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-9722","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/pages\/9722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/users\/52"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/comments?post=9722"}],"version-history":[{"count":4,"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/pages\/9722\/revisions"}],"predecessor-version":[{"id":9762,"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/pages\/9722\/revisions\/9762"}],"up":[{"embeddable":true,"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/pages\/246"}],"wp:attachment":[{"href":"https:\/\/www.sas.rochester.edu\/bio\/labs\/gorbunova\/wp-json\/wp\/v2\/media?parent=9722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}