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NIH Frontiers in Data Science Lecture Series: Translating from Bench to Bedside and Back – Challenges and Opportunities from a Data Science Perspective

April 05, 2016

The Office of the Associate Director for Data Science invites you to attend the following lecture as part of the NIH Frontiers in Data Science Lecture Series.

TITLE: "Translating from Bench to Bedside and Back – Challenges and Opportunities from a Data Science Perspective"

SPEAKER: John Shon, PhD

DATE: Tuesday, April 5, 2016, 1pm

LOCATION: Natcher Conference Center - Building 45, Room F1/F2

Lecture will be videocast via http:

ABSTRACT: As the cost of sequencing decreases, the generation of sequence data, and more importantly, genetic variation data, increases at a rate that exceeds our ability to fully understand it.  The data is also increasingly being generated in clinical contexts, providing the potential to enlighten our mechanistic understanding of disease and therapy.  From a data science perspective, Dr. Shon will describe how research and clinical operational  contexts both facilitate and limit the use of next generation sequencing data for discovery, clinical care, and translational research purposes.  Dr. Shon will also review promising approaches coupling the generation of NGS data with clinical data for the systematic application of translational knowledge for precision medicine.

ABOUT THE SPEAKER: John Shon is VP of Bioinformatics and Data Sciences at Illumina.  In this role he leads a global team of bioinformatics scientists in developing algorithms and methods for Illumina NGS instruments and assays.  As part of the Enterprise Informatics business unit, he also leads bioinformatics for clinical interpretation and translational informatics software.  Prior to Illumina, Dr. Shon has over a decade of experience in large pharmaceutical companies, most recently as VP of Informatics, Research IT and External Innovation at Janssen Pharmaceuticals (a division of J&J) where he supported R&D, clinical development and Janssen Diagnostic’s teams. At Roche, Dr. Shon led informatics groups in translational research for target discovery, biomarker selection, drug safety and personalized healthcare.


Individuals with disabilities who need Sign Language Interpreters and/or reasonable accommodation to participate in this event should contact Kristan Brown, at or 301-402-9818, and/or the Federal Relay (1-800-877-8339) at least 5 business days prior to the event.

Category: Talks