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The NIH Frontiers in Data Science Lecture Series

January 29, 2016

The NIH Frontiers in Data Science Lecture Series presents:

TITLE:  High-Performance Integrated Virtual Environment (HIVE): A regulatory NGS data analysis platform

DATE: Friday, January 29 2016, 10:00AM – 11:00AM

LOCATION: NIH Main Campus, Building 35A Room 640.

The event will be broadcasted live at https://urldefense.proofpoint.com/v2/url?u=https-3A__videocast.nih.gov_summary.asp-3Flive-3D18299-26bhcp-3D1&d=BQIFaQ&c=kbmfwr1Yojg42sGEpaQh5ofMHBeTl9EI2eaqQZhHbOU&r=tOwn0oN_8RuetsY3XUy2RT8lwZHs9dSONnHg_ZCpCbM&m=5WcExE9vMY6Ks85XqBHBs2EkITIynSKvs23R173-fco&s=z4ADdwFjaXRDedJPOxo6twsq7WD8a6lQD6P4Z79IzlM&e=

 

SPEAKERS: Vahan Simonyan, Ph.D, HIVE Lead Scientist at FDA; Raja Mazumder, Ph.D., HIVE Lead Scientist at GW

ABSTRACT:

Abundance of miscellaneous high performance computational platforms available across academia, healthcare industry, and in government organizations isn't doing much to close the gap between research and regulatory analytics. Extra iterations for drug, device and biologics approval process are causing a significant cost increase for medical product development. High-Performance Integrated Virtual Environment (HIVE) co-developed by FDA and GW presents a great opportunity for serving as a bridge. It is authorized as a regulatory NGS data analysis platform and provides unique capability for healthcare stakeholders to look into NGS data from regulatory perspective of FDA.

As a distributed storage and computation environment and a multicomponent cloud infrastructure, HIVE provides secure web access for authorized users to deposit, retrieve, annotate, and compute on biomedical big data, and to analyze the outcomes using web interface visual environments appropriately built in collaboration with internal and external end users. In addition to the initial HIVE applications to next generation sequencing, the current universe of HIVE projects covers tailor-made applications involving dimensionality analysis, federated and integrated data mapping, modeling and simulations that are applicable to basic research, biostatistics, epidemiology, clinical studies, post-market evaluation, manufacturing consistency, environmental metagenomics, outbreak detection, and more.

ABOUT THE SPEAKERS:

Vahan Simonyan, Ph.D. is the HIVE Lead Scientist at FDA, an author to more than 50 scientific publications in quantum physics and chemistry, nanotechnology, biotechnology, population dynamics, and bioinformatics.

The technology developed by Dr. Simonyan and the code-base donated to US government has launched HIVE at FDA. This resulted in an enormous success in the form of the regulatory compliant R&D IT platform capable of handling peta-scale data from sequencing projects, post-market analytics, clinical and preclinical data analysis. Currently Dr. Simonyan's collaborations span the scope of +80 medium to large research and regulatory projects with scientists from government organizations, large healthcare consortia and academia.

Raja Mazumder, Ph.D. is the HIVE Lead Scientist at GW, an Associate Professor of Biochemistry and Molecular Medicine and the Director of The McCormick Genomic & Proteomic Center at The George Washington University (GW). Prior to joining GW, Raja was a faculty at Georgetown University (GU) where he worked on the UniProt project as a Team Lead with colleagues from European Bioinformatics Institute and Swiss Institute of Bioinformatics. Prior to GU, Raja worked at the National Center for Biotechnology Information (NCBI) as a Bioinformatics Scientist.

REASONABLE ACCOMODATION:

Individuals with disabilities who need Sign Language Interpreters and/or reasonable accommodation to participate in this event should contact Sonynka Ngosso, at sonynka.ngosso@nih.gov or 301-402-9816, and/or the Federal Relay (1-800-877-8339) at least 5 business days prior to the event.

 

 

 

Category: Talks